Document Detail


Bilateral atrophy of the frontal and temporal lobes in schizophrenic patients with Capgras syndrome: a case-control study using computed tomography.
MedLine Citation:
PMID:  2380157     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The computed tomographic scans of 12 patients with Capgras syndrome and 12 matched controls were blindly assessed. A variety of statistical comparisons between the two groups consistently showed that patients with Capgras syndrome had significantly more bilateral frontal and temporal lobe atrophy. Capgras syndrome may be associated with dysfunction of these areas. Interestingly, all of the index patients had paranoid schizophrenia, and these results suggest the hypothesis that in some schizophrenic patients the presence of Capgras syndrome may be a marker for the coexistence of a focal idiopathic neurodegenerative process that preferentially affects the anterior cerebrum bilaterally.
Authors:
A B Joseph; D H O'Leary; H G Wheeler
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  51     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-09-11     Completed Date:  1990-09-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  322-5     Citation Subset:  IM    
Affiliation:
Department of Psychiatry, Harvard Medical School, Boston, MA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Atrophy / pathology
Capgras Syndrome / complications,  pathology,  radiography*
Female
Frontal Lobe / pathology*,  radiography
Humans
Male
Middle Aged
Psychotic Disorders / radiography*
Schizophrenia, Paranoid / complications,  pathology,  radiography*
Temporal Lobe / pathology*,  radiography
Tomography, X-Ray Computed*
Comments/Corrections
Comment In:
J Clin Psychiatry. 1991 Jan;52(1):43   [PMID:  1988421 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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