Document Detail


Bilateral adrenalectomy for Cushing's syndrome: a comparison between laparoscopy and open surgery.
MedLine Citation:
PMID:  15505989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report our experience with bilateral adrenalectomy for treatment of Cushing's syndrome and we compare the outcome of laparoscopy with open surgery in terms of effectiveness and safety. A series of 23 patients underwent bilateral adrenalectomy for treatment of Cushing's syndrome [Cushing's disease in 16, ectopic ACTH syndrome in 2, and ACTH-independent macronodular adrenal hyperplasia (AIMAH) in 5 cases]. From 1993 to 1996, all patients were treated using an open approach (Group A), while from 1997 all patients were treated using a transperitoneal laparoscopic approach (Group B). The comparison between the 2 groups was performed considering patients characteristics, operative times, blood losses, intraoperative and post-operative complications, analgesic consumption, post-operative hospital stay and recovery. Open surgery was performed in 10 patients and laparoscopy in 13 patients. No significant difference was recorded between the two groups as to patients' characteristics and complications. Mean operative time was significantly increased in Group B, while post-operative hospital stay was significantly longer in Group A. Laparoscopic bilateral adrenalectomy can be safely and effectively employed to treat Cushing's syndrome. However, long operatives times may represent a limitation especially in high risk patients.
Authors:
F Porpiglia; C Fiori; S Bovio; P Destefanis; A Alì; C Terrone; D Fontana; R M Scarpa; A Tempia; M Terzolo
Related Documents :
14674719 - The treatment of de novo acromegalic patients with octreotide-lar: efficacy, tolerabili...
15671089 - Short-term effects of growth hormone (gh) treatment or deprivation on cardiovascular ri...
571599 - Sustained effect of human growth hormone therapy on children with intrauterine growth r...
19147599 - Long-term treatment of acromegalic patients resistant to somatostatin analogues with th...
17451339 - Laparoscopic retroperitoneal nephrectomy for giant hydronephrosis: when simple nephrect...
11677989 - Prospects in medical management of echinococcus granulosus.
3056209 - Postoperative pain relief; a new approach: narcotics compared with non-steroidal anti-i...
17205239 - Total lumbar disc replacement in athletes: clinical results, return to sport and athlet...
18423529 - Prehemorrhage statin use and the risk of vasospasm after aneurysmal subarachnoid hemorr...
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  27     ISSN:  0391-4097     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:    2004 Jul-Aug
Date Detail:
Created Date:  2004-10-27     Completed Date:  2005-02-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  654-8     Citation Subset:  IM    
Affiliation:
Division of Urology II, Department of Clinical and Surgical Sciences, San Giovanni Battista Hospital, Italy. porpiglia@libero.it
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adrenalectomy / methods*
Adult
Cushing Syndrome / surgery*
Female
Humans
Laparoscopy*
Laparotomy
Length of Stay
Male
Middle Aged
Postoperative Complications*
Retrospective Studies
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Anthropometric, hormonal and biochemical differences in lean and obese women before and after menopa...
Next Document:  There are no acute cardiac effects of a single iv dose of human ghrelin in severe growth hormone def...