Document Detail

Bilateral MR volumetry of the amygdala in chronic PTSD patients.
MedLine Citation:
PMID:  17058525     Owner:  NLM     Status:  MEDLINE    
Posttraumatic stress disorder (PTSD) patients experience symptoms which implicate dysfunction of emotional memory circuits, and possible damage of the amygdala. Laterality differences in activity of the amygdala have been reported in PTSD patients, with presumed adaptive plasticity in the hippocampus and the amygdala. The aim of this study was to investigate possible interhemispheric differences of amygdalar volume in chronic PTSD patients, with calculation of right-to-left volume ratios. Bilateral magnetic resonance (MR) volumetry was applied in 11 chronic PTSD patients. The mean right amygdalar volume of our patients was significantly smaller than the left one (p = 0.031), with the right-to-left volume ratio of 0.96 +/- 0.06. This tendency towards smaller right amygdala may be an acquired effect as a result of stress-induced plasticity, however we can not exclude the possibility of a predisposing condition.
Goran Pavlisa; Jurica Papa; Ladislav Pavić; Gordana Pavlisa
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Collegium antropologicum     Volume:  30     ISSN:  0350-6134     ISO Abbreviation:  Coll Antropol     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-10-23     Completed Date:  2006-11-02     Revised Date:  2009-02-04    
Medline Journal Info:
Nlm Unique ID:  8003354     Medline TA:  Coll Antropol     Country:  Croatia    
Other Details:
Languages:  eng     Pagination:  565-8     Citation Subset:  IM    
Clinical Institute of Diagnostic and Interventional Radiology, University Hospital Center of Zagreb, Medical School, University of Zagreb, Zagreb, Croatia.
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MeSH Terms
Amygdala / pathology*
Case-Control Studies
Chronic Disease
Functional Laterality*
Magnetic Resonance Spectroscopy
Middle Aged
Stress Disorders, Post-Traumatic / physiopathology*

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