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Bilateral Complete Labyrinthine Aplasia with Bilateral Internal Carotid Artery Aplasia, Developmental Delay, and Gaze Abnormalities: A Presumptive Case of a Rare HOXA1 Mutation Syndrome.
MedLine Citation:
PMID:  20075099     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
SUMMARY: The human HOXA1 mutation syndromes commonly present with abnormalities of the inner ear and ICAs. Previous cases describe varying degrees of hypoplasia or aplasia of the affected structures, often with asymmetric involvement. We present imaging findings documenting complete absence of the ICAs bilaterally with bilateral CLA, which, to our knowledge, has not been previously reported.
Authors:
M J Higley; T W Walkiewicz; J H Miller; J G Curran; R B Towbin
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Publication Detail:
Type:  Journal Article     Date:  2010-01-14
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  32     ISSN:  1936-959X     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E23-5     Citation Subset:  IM    
Affiliation:
Department of Radiology, Phoenix Children's Hospital, Phoenix, Arizona.
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