Document Detail

Bilateral comparison of conventional epithelial laser in situ keratomileusis and lamellar epithelial debridement for moderate to high myopia.
MedLine Citation:
PMID:  20508509     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To compare early postoperative pain and visual outcomes after conventional epithelial laser in situ keratomileusis and lamellar epithelial debridement (LED) procedures used to treat myopia. METHODS: Prospective bilateral comparison between conventional epithelial laser in situ keratomileusis, in which the epithelial flap was repositioned, and LED, in which the epithelial sheet was removed, was designed. Eighteen patients were included. The Amadeus II Epi-Keratome (Advanced Medical Optics, Santa Ana, CA) and the Zywave Z100 instrument (Bausch & Lomb, Rochester, NY) were used in both groups. Therapeutic contact lenses (Focus 1-2 Week; CIBA Vision, Duluth, GA) were applied. To control postoperative pain, Durogesic D-trans patches 12 mug/h (Janssen Pharmaceutica, Piscataway, NJ) were prescribed. During the early postoperative period, pain, uncorrected visual acuity (UCVA), and time of epithelial healing were recorded. Late visual outcomes including UCVA and corneal haze were examined during follow-up over 6 months. RESULTS: The pain score at the fourth postoperative day was significantly lower in the LED group compared with the conventional group (P < 0.05). The UCVA in the LED group was significantly better than that in the conventional group during the early postoperative period. Mean epithelial healing time was significantly longer in the conventional group (5.33 +/- 2.03 days) than that in the LED group (3.56 +/- 0.86 days). There was no between-group difference in corneal haze development or UCVA during the 6-month follow-up period. CONCLUSION: Patients in the LED group experienced less postoperative pain, faster corneal healing, and quicker visual recovery during the early postoperative period, compared with those the conventional group.
Jae-Hyung Kim; Taehyung Lim; Hee Gyung Lee; Jae Yong Kim; Myoung Joon Kim; Hungwon Tchah
Related Documents :
18556939 - Staged automated lamellar keratoplasty for anterior stromal corneal dystrophies.
17698749 - Evaluation of the relationship between ablation diameter, pupil size, and visual functi...
10966949 - Recombinant tissue plasminogen activator following paediatric cataract surgery.
15256989 - Frequency, distribution, and outcome of keratoplasty for corneal dystrophies at a terti...
19842609 - Prospective randomized trial of limbal relaxing incisions combined with microincision c...
19563369 - Psychometric properties of visual functioning index using rasch analysis.
17720079 - Safety and efficacy of intraoperative intravitreal injection of triamcinolone acetonide...
17469029 - Impact of the degree of hydronephrosis on the efficacy of in situ extracorporeal shock-...
17382609 - Treatment of life-threatening type i refractory coeliac disease with long-term infliximab.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cornea     Volume:  29     ISSN:  1536-4798     ISO Abbreviation:  Cornea     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-27     Completed Date:  2010-10-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8216186     Medline TA:  Cornea     Country:  United States    
Other Details:
Languages:  eng     Pagination:  853-7     Citation Subset:  IM    
Department of Ophthalmology, University of Ulsan College of Medicine, Seoul, Korea.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Debridement / methods*
Epithelium, Corneal / surgery*
Functional Laterality
Keratomileusis, Laser In Situ / methods*
Lasers, Excimer / therapeutic use*
Myopia, Degenerative / physiopathology,  surgery*
Pain Measurement
Pain, Postoperative / diagnosis
Prospective Studies
Surgical Flaps
Visual Acuity / physiology
Wound Healing / physiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  UV Absorbance of a Bioengineered Corneal Stroma Substitute in the 240-400 Range.
Next Document:  Effect of Intravitreal Ranibizumab on Corneal Endothelium in Age-Related Macular Degeneration.