Document Detail

Bigger families fare better: a novel method to estimate rater contrast effects in parental ratings on ADHD symptoms.
MedLine Citation:
PMID:  23053732     Owner:  NLM     Status:  MEDLINE    
Many twin studies on parental ratings of attention deficit hyperactivity disorder (ADHD) symptoms report low or negative DZ correlations. The observed differences in MZ and DZ variances indicate sibling contrast effects, which appear to reflect a bias in parent ratings. Knowledge of the factors that contribute to this rater contrast effect is, however, limited. Using parent-rated ADHD symptoms from the Twins' Early Development Study and a novel application of a twin model, we explored a range of socio-demographic variables (ethnicity, socio-economic status, and family size), as potential contributors to contrast effects and their interactive effect with gender composition of twin pairs. Gender did moderate contrast effects but only in DZ opposite-sex twin pairs. Family size also showed a moderating effect on rater contrast effects, which was further modified by gender. We further observed an effect of rating scale, with the DSM-IV ADHD subscale of the Revised Conners' Parent Rating Scale more resistant to contrast effects than shorter scales of ADHD symptoms. The improved identification of situations where the accuracy of the most common informant of childhood ADHD symptoms-parents-is compromised as a result of rater bias, might have implications for future research on ADHD.
R Pinto; F Rijsdijk; A C Frazier-Wood; P Asherson; J Kuntsi
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Twin Study     Date:  2012-09-15
Journal Detail:
Title:  Behavior genetics     Volume:  42     ISSN:  1573-3297     ISO Abbreviation:  Behav. Genet.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-10-11     Completed Date:  2013-03-06     Revised Date:  2014-10-14    
Medline Journal Info:
Nlm Unique ID:  0251711     Medline TA:  Behav Genet     Country:  United States    
Other Details:
Languages:  eng     Pagination:  875-85     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Attention Deficit Disorder with Hyperactivity / diagnosis*,  genetics*
Child, Preschool
Diagnostic and Statistical Manual of Mental Disorders
Family Characteristics*
Observer Variation*
Sex Factors
Twins, Dizygotic
Twins, Monozygotic
Grant Support
G0500079//Medical Research Council; G0500079.//Medical Research Council

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The nitrone spin trap 5,5-dimethyl-1-pyrroline N-oxide affects stress response and fate of lipopolys...
Next Document:  Genetic parameters for fitness and neonatal behavior traits in sheep.