Document Detail

Bifocal sclerosing osteosarcoma: unusual presentation and course.
MedLine Citation:
PMID:  9765139     Owner:  NLM     Status:  MEDLINE    
Multifocal osteosarcoma is uncommon. Long-term survival of an incompletely treated case is exceptional. We report an unusual case of bifocal sclerosing osteosarcoma in a 38-year-old women that involved the left ilium and right proximal femur. The femoral lesion was resected. The tumor in the left ilium was not treated. She did not receive chemotherapy and has been free of metastases for 7 years. Recently, growth of the pelvic osteosarcoma has resulted in vascular compression and edema of the lower extremity. The patient's alkaline phosphatase has been elevated throughout. The tumor was HMB-45 positive, which has not been previously reported in osteosarcoma. The pathogenesis of multifocal osteosarcoma is discussed.
L Abramovici; G C Steiner; Z Rosenberg; S Kenan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Skeletal radiology     Volume:  27     ISSN:  0364-2348     ISO Abbreviation:  Skeletal Radiol.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-12-21     Completed Date:  1998-12-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7701953     Medline TA:  Skeletal Radiol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  449-52     Citation Subset:  IM    
Department of Pathology and Laboratory Medicine, Hospital for Joint Diseases, New York, NY 10009, USA.
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MeSH Terms
Alkaline Phosphatase / blood
Bone Neoplasms / diagnosis*,  surgery
Diagnostic Imaging
Femoral Neoplasms / diagnosis*,  surgery
Femur Head / pathology
Ilium* / pathology
Osteosarcoma / diagnosis*,  surgery
Reg. No./Substance:
EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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