Document Detail

Bicuspid aortic valve: a literature review and its impact on sport activity.
MedLine Citation:
PMID:  18296454     Owner:  NLM     Status:  MEDLINE    
The bicuspid aortic valve (BAV) is the most common congenital cardiac malformation. A literature search was performed using the key words 'bicuspid aortic valve', 'pathophysiology', 'exercise' and 'training'. BAV is the result of a complex developmental process where several genes seem to lead to abnormal valvulogenesis. Complications associated with BAV include aortic stenosis (AS) and regurgitation, infective endocarditis and aortic dilation and dissection. Moreover, BAV may be associated with other cardiovascular anomalies, mainly aortic coarctation. There is greater awareness of BAV in the young population who practice sport, with an increasing interest on the impact of regular and competitive exercise on athletes with BAV. The early identification of BAV through pre-participation screening is of paramount importance, and the justification of the more appropriate diagnostic methods is still an area of debate. A normally functioning BAV usually does not represent a limit for practising sport. The stress of regular and intense exercise on an abnormal aortic valve may favour its early deterioration and accelerate the development of complications. Therefore, athletes with BAV warrant regular follow-up, which should include echocardiographic assessment at least every year. The eligibility for participation and ability to continue to practise competitive sports in athletes with BAV cannot be generalized, but needs to be individualized depending on age, severity of lesions and type of sport. Further studies are required to elucidate the impact of physical training and competitive sports on the natural course of the BAV.
Paola De Mozzi; Umile Giuseppe Longo; Giorgio Galanti; Nicola Maffulli
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-02-21
Journal Detail:
Title:  British medical bulletin     Volume:  85     ISSN:  1471-8391     ISO Abbreviation:  Br. Med. Bull.     Publication Date:  2008  
Date Detail:
Created Date:  2008-03-12     Completed Date:  2008-10-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376542     Medline TA:  Br Med Bull     Country:  England    
Other Details:
Languages:  eng     Pagination:  63-85     Citation Subset:  IM    
Department of Medicine, , University Hospital of North Staffordshire, Keele University School of Medicine, Stoke on Trent, ST4 7LN, UK.
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MeSH Terms
Aortic Valve / abnormalities*,  physiopathology
Exercise / physiology*
Heart Valve Diseases / diagnosis,  etiology*,  physiopathology
Sports / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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