Document Detail

Bicoid mRNA diffusion as a mechanism of morphogenesis in Drosophila early development.
MedLine Citation:
PMID:  25433559     Owner:  NLM     Status:  In-Data-Review    
We show that mRNA diffusion is the main morphogenesis mechanism that consistently explains the establishment of Bicoid protein gradients in the embryo of Drosophila, contradicting the current view of protein diffusion. Moreover, we show that if diffusion for both bicoid mRNA and Bicoid protein were assumed, a steady distribution of Bicoid protein with a constant concentration along the embryo would result, contradicting observations.
Rui Dilão
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Publication Detail:
Type:  Journal Article     Date:  2014-10-23
Journal Detail:
Title:  Comptes rendus biologies     Volume:  337     ISSN:  1768-3238     ISO Abbreviation:  C. R. Biol.     Publication Date:  2014 Dec 
Date Detail:
Created Date:  2014-12-01     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101140040     Medline TA:  C R Biol     Country:  France    
Other Details:
Languages:  eng     Pagination:  679-82     Citation Subset:  IM    
Copyright Information:
Copyright © 2014 Académie des sciences. Published by Elsevier SAS. All rights reserved.
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