Document Detail

Bickerstaff brainstem encephalitis associated with Mycoplasma pneumoniae infection.
MedLine Citation:
PMID:  16948943     Owner:  NLM     Status:  MEDLINE    
Bickerstaff brainstem encephalitis is a clinical syndrome of ophthalmoplegia, cerebellar ataxia, and central nervous system signs and is associated with the presence of anti-GQ1b antibodies. There is a clinical continuum between Bickerstaff brainstem encephalitis and Miller Fisher syndrome. We describe the case of an 11-year-old boy with encephalopathy, external ophthalmoplegia, brainstem signs, and ataxia with raised titers of anti-GQ1b antibodies. He presented following a respiratory illness and had laboratory evidence of recent infection with Mycoplasma pneumoniae. M pneumoniae infection has been associated with both Bickerstaff brainstem encephalitis and Miller Fisher syndrome. This is only the second case in the literature of Bickerstaff brainstem encephalitis with raised titers of anti-GQ1b antibodies described in association with M pneumoniae infection. The patient responded to intravenous immunoglobulin administration.
Andrew C Steer; Mike Starr; Andrew J Kornberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  21     ISSN:  0883-0738     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-09-04     Completed Date:  2006-11-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  533-4     Citation Subset:  IM    
Infectious Diseases Unit, Department of General Medicine, Royal Children's Hospital, Flemington Road, Parkville, Melbourne, Victoria 3052, Australia.
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MeSH Terms
Brain Stem*
Encephalitis / diagnosis,  microbiology*,  therapy
Mycoplasma Infections / diagnosis*,  therapy
Mycoplasma pneumoniae*

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