Document Detail


Bias in psychiatric case-control studies: literature survey.
MedLine Citation:
PMID:  17329739     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Case-control studies are vulnerable to selection and information biases which may generate misleading findings. AIMS: To assess the quality of methodological reporting of case-control studies published in general psychiatric journals. METHOD: All the case-control studies published over a 2-year period in the six general psychiatric journals with impact factors of more than 3 were assessed by a group of psychiatrists with training in epidemiology using a structured assessment devised for the purpose. The measured study quality was compared across type of exposure and journal. RESULTS: The reporting of methods in the 408 identified papers was generally poor, with basic information about recruitment of participants often absent. Reduction of selection bias was described best in the "pencil and paper" studies and worst in the genetic studies. Neuroimaging studies reported the most safeguards against information bias. Measurement of exposure was reported least well in studies determining the exposure with a biological test. CONCLUSIONS: Poor reporting of recruitment strategies threatens the validity of reported results and reduces the generalisability of studies.
Authors:
William Lee; Jonathan Bindman; Tamsin Ford; Nick Glozier; Paul Moran; Robert Stewart; Matthew Hotopf
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The British journal of psychiatry : the journal of mental science     Volume:  190     ISSN:  0007-1250     ISO Abbreviation:  Br J Psychiatry     Publication Date:  2007 Mar 
Date Detail:
Created Date:  2007-03-01     Completed Date:  2007-07-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0342367     Medline TA:  Br J Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  204-9     Citation Subset:  IM    
Affiliation:
Department of Psychological Medicine, King's College London, Institute of Psychiatry, Weston Education Centre, 10 Cutcombe Road, London SE5 9RJ, UK.
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MeSH Terms
Descriptor/Qualifier:
Bias (Epidemiology)*
Case-Control Studies*
Observer Variation
Periodicals as Topic / statistics & numerical data*
Psychiatry / statistics & numerical data*

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