Document Detail


Bias in genetic evaluations by records of cows treated with bovine somatotropin.
MedLine Citation:
PMID:  11104285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Records from Dairy Records Management Systems in Raleigh were used to estimate effects of bovine somatotropin (bST) treatment and to predict breeding values for milk production traits. The data comprised 5245 test-day records of bST-treated cows and 126,223 test-day records of untreated cows in first lactation for milk, fat, and protein yields. Fixed effects of bST treatment were estimated from test-day animal models with herd-test-date as another fixed factor. Percentage increases due to bST treatment ranged from 7 to 8% for test-day milk, fat, and protein yields. Random regression coefficients for additive genetic and permanent environmental effects were included in the model. To assess the potential for bias in genetic evaluations when some and not all cows are treated with bST, breeding values predicted by the test-day model with and without effects of bST treatment were compared for cows and sires. Correlations between breeding values predicted from models with and without effects of bST treatment were 0.99. However, relatively large bias was found for individual animals. This result suggests that bias in genetic evaluation caused by ignoring bST treatment may be significant.
Authors:
S Tsuruta; J F Keown; L D Van Vleck; I Misztal
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of dairy science     Volume:  83     ISSN:  0022-0302     ISO Abbreviation:  J. Dairy Sci.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-02-28     Completed Date:  2001-03-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  2985126R     Medline TA:  J Dairy Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  2650-6     Citation Subset:  IM    
Affiliation:
Department of Animal Science, University of Nebraska, Lincoln 68583-0908, USA. shogo@arches.uga.edu
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MeSH Terms
Descriptor/Qualifier:
Animals
Bias (Epidemiology)*
Cattle / genetics*
Dairying / methods
Female
Growth Hormone / pharmacology*
Lactation / genetics,  physiology*
Milk / chemistry,  drug effects*,  secretion*
Records as Topic
Regression Analysis
Chemical
Reg. No./Substance:
9002-72-6/Growth Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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