| BiPAP in acute respiratory failure due to myasthenic crisis may prevent intubation. | |
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MedLine Citation:
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PMID: 12451217 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Noninvasive mechanical ventilation using bilevel positive pressure ventilation (BiPAP) has not been studied in acute respiratory failure caused by MG. Eleven episodes in nine patients were initially managed with BiPAP, and endotracheal intubation was avoided in seven of these trials. Presence of hypercapnia (PaCO2 greater than 50 mm Hg) at onset predicted BiPAP failure and subsequent intubation. Results of this preliminary study suggest that a trial of BiPAP may prevent intubation in patients with myasthenic crisis without overt hypercapnia. |
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Authors:
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Alejandro Rabinstein; Eelco F M Wijdicks |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Neurology Volume: 59 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 2002 Nov |
Date Detail:
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Created Date: 2002-11-26 Completed Date: 2002-12-17 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: United States |
Other Details:
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Languages: eng Pagination: 1647-9 Citation Subset: AIM; IM |
Affiliation:
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Neurologic-Neurosurgical ICU, Saint Mary's Hospital, Mayo Medical Center, Rochester, MN 55905, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Blood Gas Analysis Humans Hypercapnia / complications Intubation, Intratracheal Myasthenia Gravis / complications* Point-of-Care Systems Positive-Pressure Respiration* Respiratory Function Tests Respiratory Insufficiency / etiology*, therapy* Retrospective Studies |
| Comments/Corrections | |
Comment In:
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Neurology. 2003 Jul 8;61(1):144; author reply 144
[PMID:
12847184
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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