Document Detail


BiDil: from another vantage point.
MedLine Citation:
PMID:  16912053     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a recent Health Affairs Web Exclusive, Pamela Sankar and Jonathan Kahn argue against the Food and Drug Administration's approval of BiDil as a new drug for the treatment of heart failure in African Americans. Their paper questions the existence of disparities between African American and other heart-failure patients and the motivations of BiDil's developers and manufacturer. The disparities are confirmed and persistent, however, and BiDil's effectiveness is proven. If the authors' logic were to prevail, patients would be denied life-saving therapy. Continued investigation will likely narrow identification of patients who will benefit.
Authors:
Gary Puckrein
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-08-15
Journal Detail:
Title:  Health affairs (Project Hope)     Volume:  25     ISSN:  1544-5208     ISO Abbreviation:  Health Aff (Millwood)     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-09-12     Completed Date:  2007-03-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8303128     Medline TA:  Health Aff (Millwood)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  w368-74     Citation Subset:  IM    
Affiliation:
National Minority Health Month Foundation in Washington, DC, USA. gpuckrein@americanvisions.com
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MeSH Terms
Descriptor/Qualifier:
African Americans / genetics*
Drug Approval*
Drug Combinations
Drug Industry
Genetic Predisposition to Disease / ethnology
Heart Failure / drug therapy*,  ethnology
Humans
Hydralazine
Isosorbide Dinitrate / therapeutic use*
Risk
United States
United States Food and Drug Administration
Vasodilator Agents / therapeutic use*
Chemical
Reg. No./Substance:
0/Drug Combinations; 0/Vasodilator Agents; 0/isosorbide-hydralazine combination; 86-54-4/Hydralazine; 87-33-2/Isosorbide Dinitrate
Comments/Corrections
Comment In:
Health Aff (Millwood). 2006 Sep-Oct;25(5):w375-7   [PMID:  16912052 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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