Document Detail


Bi-annual surge of Crimean-Congo haemorrhagic fever (CCHF): a five-year experience.
MedLine Citation:
PMID:  15696649     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the peak time of outbreak of Crimean-Congo haemorrhagic fever (CCHF) and to highlight the disease-specific areas in the Balochistan province of Pakistan. DESIGN: A hospital-based case-series study. PLACE AND DURATION: A five-year study was conducted by the Department of Pathology in collaboration with the Department of Medicine, Sandeman Provincial Teaching Hospital, Quetta, Balochistan, Pakistan, from 1 March 1997 to 28 February 2002. PATIENTS AND METHODS: A total of 135 cases were included in the study based on a high index of suspicion of CCHF. The mean age was 33.5+/-18.7 years. Two sets of blood samples were drawn on admission; one set was sent for urgent routine investigations while the other was sent to CDC, Atlanta, USA, for confirmation. RESULTS: The study showed that CCHF was more common between March and May and again, between August and October, depicting a bi-annual surge. Out of 135 suspected cases, 83 (61.4%) were confirmed to have CCHF and were given platelet concentrate and ribavirin. It ws observed that CCHF was more common in specific areas of the province. CONCLUSIONS: It is essential to raise the level of knowledge regarding CCHF, especially in disease-specific areas, focussing on the peak outbreak periods.
Authors:
Azeem S Sheikh; Aqleem A Sheikh; Nadeem S Sheikh; Rafi-U-Shan; Mohammad Asif; Farhan Afridi; M Tarik Malik
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases     Volume:  9     ISSN:  1201-9712     ISO Abbreviation:  Int. J. Infect. Dis.     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2005-02-07     Completed Date:  2005-03-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610933     Medline TA:  Int J Infect Dis     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  37-42     Citation Subset:  IM    
Affiliation:
Department of Medicine, Shaikh Zayed Hospital, FPGMI, Lahore, Pakistan. drazeemsheikh@hotmail.com
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Antiviral Agents / therapeutic use
Disease Outbreaks
Female
Hemorrhagic Fever, Crimean / diagnosis,  drug therapy,  epidemiology*
Humans
Male
Middle Aged
Pakistan / epidemiology
Ribavirin / therapeutic use
Seasons
Chemical
Reg. No./Substance:
0/Antiviral Agents; 36791-04-5/Ribavirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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