Document Detail

Beyond low-density lipoprotein cholesterol. A perspective on low high-density lipoprotein disorders and Lp(a) lipoprotein excess.
MedLine Citation:
PMID:  8651835     Owner:  NLM     Status:  MEDLINE    
Evidence supports the involvement of 2 common dyslipidemias---low high-density lipoprotein disorders and Lp(a) lipoprotein excess--in coronary heart disease. Until clinical trials determine whether specific therapeutic interventions can prevent the occurrence and recurrence of coronary heart disease in patients with these dyslipidemias, the implementation of cholesterol-lowering guidelines can provide a reasonable way to manage low high-density lipoprotein disorders and to identify specific categories of patients who may be at particularly high risk for premature coronary heart disease. Empiric treatment guidelines are suggested for low high-density lipoprotein disorders and Lp(a) lipoprotein excess in order to foster further discussion and validation by clinical trial data.
R S Rosenson
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Archives of internal medicine     Volume:  156     ISSN:  0003-9926     ISO Abbreviation:  Arch. Intern. Med.     Publication Date:  1996 Jun 
Date Detail:
Created Date:  1996-07-25     Completed Date:  1996-07-25     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0372440     Medline TA:  Arch Intern Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1278-84     Citation Subset:  AIM; IM    
Preventive Cardiology Center, Rush-Presbyterian-St Luke's Medical Center, Chicago, Ill., USA.
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MeSH Terms
Cholesterol, HDL / blood*
Cholesterol, LDL / blood*
Coronary Disease / blood,  etiology
Hyperlipidemias / blood,  complications
Lipoprotein(a) / blood*
Reg. No./Substance:
0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Lipoprotein(a)

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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