| Beyond dyssynchrony in cardiac resynchronisation therapy. | |
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MedLine Citation:
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PMID: 18625794 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac resynchronisation therapy (CRT) in the form of biventricular pacing has emerged as a therapeutic option for patients with refractory heart failure. Patient selection and optimisation for CRT is based on the measurement of electromechanical ventricular dyssynchrony by electrocardiogram and echocardiographic techniques. The final common pathway for raising cardiac output on exertion is to minimise isovolumic time and maximise useful diastolic filling time, but correction of dyssynchrony alone may not lead to global improvement in about one-third of patients. Insights into pressure relations and abnormal timing, as well as clinical management, may hold the key to optimum outcome. |
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Authors:
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R Chung; R Sutton; M Y Henein |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Heart (British Cardiac Society) Volume: 94 ISSN: 1468-201X ISO Abbreviation: Heart Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-07-15 Completed Date: 2008-08-07 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9602087 Medline TA: Heart Country: England |
Other Details:
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Languages: eng Pagination: 991-4 Citation Subset: AIM; IM |
Affiliation:
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Royal Brompton Hospital, London, UK. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Cardiac Pacing, Artificial
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methods* Heart Failure / complications, therapy* Humans Patient Selection Treatment Failure Ventricular Dysfunction, Left / etiology, therapy, ultrasonography |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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