Document Detail

Bevacizumab maintenance in metastatic colorectal cancer: How long?
MedLine Citation:
PMID:  25405197     Owner:  NLM     Status:  PubMed-not-MEDLINE    
The management of patients with non-progressive metastatic colorectal cancer after six months of treatment has not yet been codified. The most relevant concerns are the effectiveness of maintenance vs discontinuation, and the tolerability of prolonged treatment. Here we report the case of a 72-year-old man affected by colorectal cancer with lung metastases who achieved a complete response after receiving capecitabine, oxaliplatin and bevacizumab for six months, and bevacizumab alone for six months. Bevacizumab was continued as maintenance regimen for more than three years. It was discontinued because of an arthroplasty. Fifty-eight months after beginning first-line treatment, the patient remains free from relapse. Adverse effects were minimal and easily controlled.
Alfonso De Stefano; Roberto Moretto; Chiara Alessandra Cella; Francesco Jacopo Romano; Lucia Raimondo; Giovanni Fiore; Francesca Di Pietro; Stefano Pepe; Sabino De Placido; Chiara Carlomagno
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of clinical cases     Volume:  2     ISSN:  2307-8960     ISO Abbreviation:  World J Clin Cases     Publication Date:  2014 Nov 
Date Detail:
Created Date:  2014-11-18     Completed Date:  2014-11-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101618806     Medline TA:  World J Clin Cases     Country:  United States    
Other Details:
Languages:  eng     Pagination:  717-23     Citation Subset:  -    
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