| Bevacizumab for macular serous neuroretinal detachment in tilted disk syndrome. | |
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MedLine Citation:
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PMID: 21151645 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background. Tilted disc syndrome (TDS) is a congenital anomaly characterized by "tilting" of the optic disc tipycally associated with myopic astigmatism, visual field defect, inferior staphyloma, and retinal pigment epithelium atrophy. Associated complications such as macular serous neuroretinal detachment are well described; however, ideal therapy for such complication is unknown. Methods. One interventional case report is hereby described. A patient affected by macular serous neuroretinal detachment-complicated tilted disk syndrome underwent a complete ophthalmic examination. Optical coherence tomography and fluorescein angiography were taken at baseline and at scheduled visits. Two intravitreal treatments of bevacizumab (avastin, 1.25 mg/0.05 mL) were performed at monthly interval. Results. At scheduled visit, one month after the second injection, OCT depicted persistence of neuroretinal detachment. Best-corrected visual acuity remain stable as well as metamorphopsia and functional discomfort. Conclusion. Clinical evidence of this brief interventional case report indicates that one patient affected by recent serous macular detachment-complicated TDS did not benefit from 2 consecutive monthly intravitreal Avastin treatments. Best-corrected visual acuity remained stable over a total observation period of 6 months. |
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Authors:
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Paolo Milani; Alfredo Pece; Luisa Pierro; Patrizio Seidenari; Paolo Radice; Antonio Scialdone |
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Publication Detail:
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Type: Journal Article Date: 2010-11-30 |
Journal Detail:
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Title: Journal of ophthalmology Volume: 2010 ISSN: 2090-0058 ISO Abbreviation: J Ophthalmol Publication Date: 2010 |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101524199 Medline TA: J Ophthalmol Country: United States |
Other Details:
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Languages: eng Pagination: 970580 Citation Subset: - |
Affiliation:
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Ospedale Fatebenefratelli-Oftalmico, Corso di Porta Nuova 23, Milan, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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