Document Detail

Better tools for assessing osteoporosis.
MedLine Citation:
PMID:  23154276     Owner:  NLM     Status:  MEDLINE    
Some 30 years ago, we applied the newly described method of dual photon absorptiometry (DPA) to demonstrate that osteoporotic women with vertebral fractures had lost substantially more bone from the vertebrae than controls. This opened a whole new field of research into the determinants of bone loss and fractures in the axial skeleton and set the stage for subsequent development of dual-energy x-ray absorptiometry (DXA) and quantitative computed tomography (QCT), which are now the standard methods for assessing osteoporosis severity and treatment efficacy.
B Lawrence Riggs; Sundeep Khosla; L Joseph Melton
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Publication Detail:
Type:  Historical Article; Journal Article; Research Support, N.I.H., Extramural     Date:  2012-12-03
Journal Detail:
Title:  The Journal of clinical investigation     Volume:  122     ISSN:  1558-8238     ISO Abbreviation:  J. Clin. Invest.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-11-16     Completed Date:  2013-02-04     Revised Date:  2013-07-11    
Medline Journal Info:
Nlm Unique ID:  7802877     Medline TA:  J Clin Invest     Country:  United States    
Other Details:
Languages:  eng     Pagination:  4323-4     Citation Subset:  AIM; IM    
Endocrine Research Unit, College of Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
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MeSH Terms
Absorptiometry, Photon / history
Bone Density
History, 19th Century
Osteoporosis / pathology,  radiography*
Tomography, X-Ray Computed / history
Grant Support

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