| Better assessment of nodal metastases by PET/CT fusion compared to side-by-side PET/CT in oesophageal cancer. | |
| | |
MedLine Citation:
|
PMID: 18630473 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Recently, positron emission tomography/computed tomography (PET/CT) has been introduced in the staging of oesophageal cancer. The impact of PET/CT fusion in comparison with side-by-side PET/CT in these tumours, was analyzed. PATIENTS AND METHODS: In 61 patients, 18-F-fluorodeoxyglucose (FDG)-PET and multidetector (md)-CT were performed within a two week interval. Software-fusion of md-CT and FDG-PET was correlated with side-by-side FDG-PET/CT reading by two independent investigators. The gold standard was the pathological outcome or clinical evidence of progression during the first year of follow-up. RESULTS: In 18 patients (18/61; 30%), nodal staging improved with software-fusion. The number of nodal metastases increased in five patients and decreased in four patients, leading to up-staging in one patient (2%) and down-staging in three patients (5%). In nine cases (15%), certainty and localization of metastases improved. However, the number of distant metastases did not change and software-fusion did not have an influence on resectability. CONCLUSION: PET/CT fusion substantially improves detection and localization of nodal metastases and may have an impact on locoregional treatment options. |
| | |
Authors:
|
Liesbeth M Schreurs; Bareld B Pultrum; Klaas P Koopmans; Christian C Verhoef; Pieter L Jager; Gooitzen M Van Dam; Henk Groen; Erik J Van Der Jagt; John Th M Plukker |
Related Documents
:
|
20965393 - Contribution of positron emission tomography in pleural disease. 20364373 - Ability of 18f-fdg pet/ct to diagnose recurrent colorectal cancer in patients with elev... 1264883 - Radiologic examination of patients with stroke. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Anticancer research Volume: 28 ISSN: 0250-7005 ISO Abbreviation: Anticancer Res. Publication Date: 2008 May-Jun |
Date Detail:
|
Created Date: 2008-07-17 Completed Date: 2008-07-29 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8102988 Medline TA: Anticancer Res Country: Greece |
Other Details:
|
Languages: eng Pagination: 1867-73 Citation Subset: IM |
Affiliation:
|
Deparments of Surgical Oncology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Esophageal Neoplasms / pathology, radionuclide imaging* Female Fluorine Radioisotopes / diagnostic use Fluorodeoxyglucose F18 / diagnostic use Humans Lymph Nodes / pathology, radionuclide imaging* Lymphatic Metastasis Male Middle Aged Neoplasm Staging Positron-Emission Tomography / methods Radiopharmaceuticals / diagnostic use Retrospective Studies Tomography, X-Ray Computed / methods |
| Chemical | |
Reg. No./Substance:
|
0/Fluorine Radioisotopes; 0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cancer chemoprevention: a summary of the current evidence.
Next Document: The expression of matrix metalloproteinases-2 and -9 and their tissue inhibitor 2 in pancreatic duct...