| The Bethesda System. Impact on reporting cervicovaginal specimens and reproducibility of criteria for assessing endocervical sampling. | |
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MedLine Citation:
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PMID: 8434497 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study examined the impact of applying the Bethesda System guidelines for specimen adequacy on cytopathologic diagnosis at the Johns Hopkins Hospital laboratory of cytopathology during a one-year period. Application of the Bethesda guidelines resulted in a 1.3% unsatisfactory rate. In addition, 3.8% of specimens were satisfactory but contained an inadequate endocervical component (IEC). Smears obtained after a cone biopsy or an initial IEC smear were IEC in 16.5% and 18.7% of cases, respectively. The IEC rate following an initial smear lacking an endocervical component was 11.8% in repeat specimens obtained with an endocervical brush as compared to 29.4% in those obtained with a spatula alone. The reproducibility of the Bethesda criteria for assessing endocervical sampling was evaluated by comparing the level of agreement between three independent reviewers examining 40 test cases. Three-way agreement was achieved in 75% of cases. Two-way agreement ranged from 80.0% to 87.5%. We conclude that implementation of the Bethesda System guidelines for assessing specimen adequacy should produce a minimal impact on cytopathologic reporting and gynecologic practice. Repeat specimens lacking an endocervical component may be encountered relatively frequently in certain subsets of patients. |
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Authors:
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M E Sherman; M Weinstein; M Sughayer; J O Cappellari; J E Orr; Y S Erozan; M H Schiffman; R J Kurman |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Acta cytologica Volume: 37 ISSN: 0001-5547 ISO Abbreviation: Acta Cytol. Publication Date: 1993 Jan-Feb |
Date Detail:
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Created Date: 1993-03-17 Completed Date: 1993-03-17 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370307 Medline TA: Acta Cytol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 55-60 Citation Subset: IM |
Affiliation:
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Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Cervix Uteri / pathology* Evaluation Studies as Topic Female Humans Middle Aged Practice Guidelines as Topic* Vaginal Smears* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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