Document Detail

Beta radiation as an adjunct to low-risk trabeculectomy.
MedLine Citation:
PMID:  11021553     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess a single dose of intraoperative beta radiation used to enhance the success rate of trabeculectomy in a population of low-risk glaucoma patients in whom antimetabolites might not be indicated. METHODS: A prospective randomized trial of 65 eyes was designed, with 31 eyes receiving 750 rads of intraoperative beta radiation (group 1), and 34 eyes receiving no supplementation (group 2). RESULTS: Mean follow-up time was 24 months. Mean postoperative intraocular pressure was 12.2 mmHg in group 1, and 13.7 mmHg in group 2 (P = 0.16). Mean decrease in intraocular pressure was 10.3 mmHg in group 1, and 9.3 mmHg in group 2 (P = 0.49). The two groups were not significantly different in terms of surgical complications. CONCLUSION: For this population of low-risk patients, there was no significant difference in outcome after applications of a single intraoperative dose of beta radiation.
R M Barnes; J S Mora; S J Best
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Clinical & experimental ophthalmology     Volume:  28     ISSN:  1442-6404     ISO Abbreviation:  Clin. Experiment. Ophthalmol.     Publication Date:  2000 Aug 
Date Detail:
Created Date:  2001-01-08     Completed Date:  2001-01-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  100896531     Medline TA:  Clin Experiment Ophthalmol     Country:  AUSTRALIA    
Other Details:
Languages:  eng     Pagination:  259-62     Citation Subset:  IM    
Ophthalmology Department, Auckland Hospital, New Zealand.
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MeSH Terms
Aged, 80 and over
Double-Blind Method
Exfoliation Syndrome / complications
Follow-Up Studies
Glaucoma, Open-Angle / etiology,  radiotherapy*,  surgery*
Intraocular Pressure
Middle Aged
Prospective Studies
Radiotherapy Dosage
Radiotherapy, Adjuvant
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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