Document Detail

Beta-glucuronidase activity of lymphocytes in the premature infant with special reference to the fetal maturation stage.
MedLine Citation:
PMID:  1203090     Owner:  NLM     Status:  MEDLINE    
Activity of beta-glucuronidase (GR) was determined cytochemically by the Hayashi et al. method on peripheral blood lymphocytes of 50 premature infants, born between 21st and 37th week gestation. The subjects studied were subtyped into group I (21st to 28th week), group II (29th to 33rd week), and group III (34th to 37th week). Absolute count of enzyme-positive lymphocytes was lower in group I, when compared with group II and III as a whole. Absolute count of GR-positive lymphocytes exhibiting granular reaction type was significantly lower in group I, when compared with other groups. Absolute counts of GR-positive cells, with both granular and diffuse, or diffuse enzymatic reaction did not differ in groups I, II and III. The results obtained indicate ontogenetic development of lysosomal granules containing GR in the lymphocyte cytoplasm in premature infants related to their fetal age.
J Lisiewicz; G Astaldi; C Bryniak
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Bollettino dell'Istituto sieroterapico milanese     Volume:  54     ISSN:  0021-2547     ISO Abbreviation:  Boll Ist Sieroter Milan     Publication Date:  1975 Oct 
Date Detail:
Created Date:  1976-03-05     Completed Date:  1976-03-05     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  17720040R     Medline TA:  Boll Ist Sieroter Milan     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  349-53     Citation Subset:  IM    
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MeSH Terms
Gestational Age
Glucuronidase / metabolism*
Infant, Newborn
Infant, Premature
Lymphocytes / enzymology*
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Reg. No./Substance:

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