Document Detail


Beta-endorphin concentration in the femoral and spermatic venous blood of males affected by varicocele.
MedLine Citation:
PMID:  1337904     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several studies in the rat indicate that opioid peptides produced in the testicular interstitial compartment can affect events in the tubular compartment. For example, it is thought that some specific functions of Sertoli cells, such as androgen-binding protein production are decreased by a paracrine mechanism. In this study ACTH beta-endorphin and cortisol were measured in the femoral and spermatic venous blood drawn from 18 patients affected by varicocele during catheterization for venous occlusion. The results showed the absence of a significant secretory gradient of beta-endorphin in the human testis and also demonstrated that this opioid is circulating at picomolar concentrations within human testis under stress conditions.
Authors:
M Mariani; M Polvani; M Federghini; M Serio
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Human reproduction (Oxford, England)     Volume:  7     ISSN:  0268-1161     ISO Abbreviation:  Hum. Reprod.     Publication Date:  1992 Nov 
Date Detail:
Created Date:  1993-03-31     Completed Date:  1993-03-31     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8701199     Medline TA:  Hum Reprod     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1414-6     Citation Subset:  IM    
Affiliation:
Department of Public Health and Biostatistics, University of Pisa, Italy.
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MeSH Terms
Descriptor/Qualifier:
Adrenocorticotropic Hormone / blood
Adult
Femoral Vein / chemistry*
Humans
Hydrocortisone / blood
Male
Phlebography
Rheology
Testis / blood supply*
Testosterone / blood
Varicocele / blood*,  diagnosis
beta-Endorphin / blood*
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone; 58-22-0/Testosterone; 60617-12-1/beta-Endorphin; 9002-60-2/Adrenocorticotropic Hormone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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