Document Detail

Beta-blockers: no longer an option for uncomplicated hypertension.
MedLine Citation:
PMID:  17999868     Owner:  NLM     Status:  MEDLINE    
Traditionally, beta-blockers, used as first-line agents to treat uncomplicated hypertension, were recommended by national and international guidelines despite a paucity of evidence regarding their cardiovascular benefit. However, evidence from recent trials and meta-analyses has questioned the use of beta-blockers as preferred agents. This article reviews the data available from clinical trials and argues that beta-blockers are less efficacious than other currently available antihypertensive agents for patients with uncomplicated hypertension.
Sripal Bangalore; Gayathri Kamalakkannan; Franz H Messerli
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Current cardiology reports     Volume:  9     ISSN:  1523-3782     ISO Abbreviation:  Curr Cardiol Rep     Publication Date:  2007 Nov 
Date Detail:
Created Date:  2007-11-16     Completed Date:  2008-02-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888969     Medline TA:  Curr Cardiol Rep     Country:  United States    
Other Details:
Languages:  eng     Pagination:  441-6     Citation Subset:  IM    
Hypertension Program, Division of Cardiology, St. Luke's-Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, NY 10019, USA.
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MeSH Terms
Adrenergic beta-Antagonists / adverse effects,  pharmacology,  therapeutic use*
Antihypertensive Agents / adverse effects,  pharmacology,  therapeutic use*
Blood Pressure / drug effects
Clinical Trials as Topic
Hypertension / drug therapy*
Risk Factors
Treatment Outcome
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Antihypertensive Agents

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