| Beta-blockers in heart failure--the evidence from clinical trials. | |
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MedLine Citation:
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PMID: 8733066 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There are good theoretical reasons for supposing that long-term treatment with a beta-blocker would improve symptoms and survival in patients with heart failure. A series of small studies have shown that beta-blockers improve haemodynamic parameters, but it is well known that these correlate poorly with symptoms. There is some evidence that exercise tolerance is also improved. Although there is so far no convincing evidence that beta-blockers prolong survival in patients with heart failure the development of a new generation of these drugs with additional vasodilating properties makes further large studies essential. |
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Authors:
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J R Hampton |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: European heart journal Volume: 17 Suppl B ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1996 Apr |
Date Detail:
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Created Date: 1996-10-01 Completed Date: 1996-10-01 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 17-20 Citation Subset: IM |
Affiliation:
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Queen's Medical Centre, University Hospital, Nottingham, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic beta-Antagonists
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therapeutic use* Cardiomyopathy, Dilated / drug therapy Clinical Trials as Topic Heart Failure / drug therapy*, physiopathology Hemodynamics / drug effects Humans Myocardial Ischemia / drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic beta-Antagonists |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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