Document Detail

Beta-adrenergic blockade in the prevention of myocardial infarction: a new theory.
MedLine Citation:
PMID:  1686459     Owner:  NLM     Status:  MEDLINE    
Beta-adrenergic blockers have a protective effect in reducing mortality in survivors of myocardial infarction. It is proposed that, in addition to their effects in reducing heart rate, blood pressure, myocardial contractility and ventricular ectopy, beta-blockers may prevent or attenuate the fracture of vulnerable atherosclerotic plaques and thereby reduce coronary thrombosis, myocardial infarction and sudden cardiac death.
W H Frishman; C M Chang
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of hypertension. Supplement : official journal of the International Society of Hypertension     Volume:  9     ISSN:  0952-1178     ISO Abbreviation:  J Hypertens Suppl     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-03-31     Completed Date:  1992-03-31     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8501422     Medline TA:  J Hypertens Suppl     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  S31-4     Citation Subset:  IM    
Albert Einstein College of Medicine, Montefiore, New York, NY 10461.
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MeSH Terms
Adrenergic beta-Antagonists / therapeutic use*
Circadian Rhythm / physiology
Coronary Artery Disease / drug therapy*,  physiopathology
Coronary Thrombosis / prevention & control*
Hemodynamics / drug effects
Myocardial Infarction / prevention & control*
Reg. No./Substance:
0/Adrenergic beta-Antagonists

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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