| Beta 2-adrenergic agonist as adjunct therapy to levodopa in Parkinson's disease. | |
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MedLine Citation:
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PMID: 8058159 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We studied the effect of the beta 2-adrenergic agonist albuterol on Parkinson's disease (PD) patients receiving chronic levodopa treatment. The albuterol-treated patients demonstrated reduced parkinsonian symptoms and an increased ability to tap their index finger between two points 20 cm apart, and were able to perform a "walk test" in 70% of their control time. Three patients currently on chronic albuterol therapy still show amelioration of their parkinsonian symptoms, and two have reduced their daily levodopa dose. This study suggests that beta 2-adrenergic agonists as adjunct therapy to levodopa may be beneficial in PD. |
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Authors:
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G M Alexander; R J Schwartzman; T A Nukes; J R Grothusen; M D Hooker |
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Publication Detail:
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Type: Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Neurology Volume: 44 ISSN: 0028-3878 ISO Abbreviation: Neurology Publication Date: 1994 Aug |
Date Detail:
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Created Date: 1994-09-12 Completed Date: 1994-09-12 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0401060 Medline TA: Neurology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1511-3 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurology, Jefferson Medical College, Philadelphia, PA 19107. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Albuterol / therapeutic use* Drug Therapy, Combination Humans Levodopa / therapeutic use* Male Middle Aged Parkinson Disease / drug therapy* |
| Grant Support | |
ID/Acronym/Agency:
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5 RO1 NS27101/NS/NINDS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Levodopa; 18559-94-9/Albuterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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