| Best practice for peripheral blood progenitor cell mobilization and collection in adults and children: results of a Società Italiana Di Emaferesi e Manipolazione Cellulare (SIDEM) and Gruppo Italiano Trapianto Midollo Osseo (GITMO) consensus process. | |
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MedLine Citation:
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PMID: 21980921 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: A large heterogeneity in current mobilization and collection practices is perceived. Moreover, recent evidence introduced novel issues into some specific topics. Optimization of the clinical practice, through the adoption of clinical practice guidelines, previously proved to reduce health care resource use. STUDY DESIGN AND METHODS: Two Italian scientific societies, Società Italiana Di Emaferesi e Manipolazione Cellulare (SIDEM) and Gruppo Italiano Trapianto Midollo Osseo (GITMO), perceived the need of hematologists and transfusionists to share a common paradigm in the setting of hematopoietic stem cell transplantation (SCT). The aim of the current position paper is to provide common definitions and criteria for mobilization and collection of peripheral blood stem cells both in autologous and in the allogeneic setting. Current international and national standards (i.e., International Society of Hematotherapy and Graft Engineering) and recommendations (i.e., European Group for Blood and Marrow Transplantation) were harmonized with the Panel recommendations. RESULTS: The Expert Panel consisted of nine members (five transfusionists and four hematologists with both clinical and scientific experience of SCT in both pediatric and adult setting) and one methodologist and first convened on April 19, 2010: they in turn agreed on the questions to be answered by the project. Available literature was reviewed by one expert and the methodologist and presented to the other members. Statements were then formulated. SIDEM and GITMO planned an informal meeting of the Panel every 2 years to discuss relevant updates and possible changes to the recommendations. CONCLUSION: The efforts of the expert panel members allowed to set up and share a common approach to the mobilization, enumeration, and collection issues in the field of both autologous and allogeneic peripheral blood SCT. |
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Authors:
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Luca Pierelli; Paolo Perseghin; Monia Marchetti; Patrizia Accorsi; Renato Fanin; Chiara Messina; Attilio Olivieri; Marco Risso; Laura Salvaneschi; Alberto Bosi; |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-7 |
Journal Detail:
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Title: Transfusion Volume: - ISSN: 1537-2995 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0417360 Medline TA: Transfusion Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2011 American Association of Blood Banks. |
Affiliation:
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From the Servizio di Immunoematologia e Trasfusionale, Azienda Ospedaliera San Camillo-Forlanini and Università di Roma-La Sapienza, Roma, Italy; Servizio Trasfusionale, UOS Aferesi e Nuove Tecnologie Trasfusionali, Azienda Ospedaliera San Gerardo, Monza, Italy; Unità di Ematologia, Divisione di Medicina Interna, Ospedale C. Massaia, Asti, Italy; Servizio di Immunoematologia e Trasfusionale, UOS Aferesi, Azienda Ospedaliera Santo Spirito, Pescara, Italy; Clinica Ematologica, Azienda Ospedaliera Universitaria and Università di Udine, Udine, Italy; Clinica di Oncoematologia Pediatrica, Azienda Ospedaliera and Università di Padova, Padova, Italy; UO Ematologia, Azienda Ospedaliera San Carlo, Potenza; Servizio di Immunoematologia e Trasfusionale, IRCCS Giannina Gaslini, Genova, Italy; Servizio di Immunoematologia e Trasfusionale, IRCCS Ospedale San Matteo and Università di Pavia, Pavia, Italy; and UO Ematologia, Azienda Ospedaliera Careggi and Università di Firenze, Firenze, Italy. |
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