Document Detail

Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range.
MedLine Citation:
PMID:  18670507     Owner:  NLM     Status:  MEDLINE    
Endoscopic imaging in tubular structures, such as the tracheobronchial tree, could benefit from imaging optics with an extended depth of focus (DOF) to accommodate the varying sizes of tubular structures across patients and along the tree within the same patient. Yet the extended DOF needs to be accomplished without sacrificing resolution while maintaining sufficient sensitivity and speed of imaging. In this Letter, we report on the measured resolution and sensitivity achieved with a custom-made micro-optic axicon lens designed to theoretically achieve an 8 mm DOF. A measured invariant resolution of approximately 8 microm is demonstrated across a 4 mm measured DOF using the micro-optic axicon while achieving an invariant sensitivity of approximately 80 dB with a 25 mW input power. Double-pass Bessel beam spectral-domain optical coherence tomography with an axicon micro-optic lens (i.e., <1 mm in diameter) is, for the first time to our knowledge, demonstrated in a biological sample demonstrating invariant resolution and signal-to-noise ratio across a 4 mm measured DOF, which is compared to Gaussian beam imaging.
Kye-Sung Lee; Jannick P Rolland
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Optics letters     Volume:  33     ISSN:  0146-9592     ISO Abbreviation:  Opt Lett     Publication Date:  2008 Aug 
Date Detail:
Created Date:  2008-08-01     Completed Date:  2008-09-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7708433     Medline TA:  Opt Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1696-8     Citation Subset:  IM    
CREOL, The College of Optics and Photonics, University of Central Florida, Orlando, Florida 32816, USA.
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MeSH Terms
Larva / anatomy & histology
Tomography, Optical Coherence / instrumentation,  methods*
Xenopus laevis / anatomy & histology,  embryology

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