| Beryllium medical surveillance at a former nuclear weapons facility during cleanup operations. | |
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MedLine Citation:
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PMID: 15354061 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Despite increasing need to remediate beryllium-contaminated buildings in industry, little is known about the magnitude of risk associated with beryllium abatement or the merits of beryllium medical surveillance for cleanup workers. We examined beryllium lymphocyte proliferation tests and reviewed medical evaluations on workers at a nuclear weapons facility during the process of decontamination and decommissioning. Of 2,221 workers, 19 (0.8%) were beryllium sensitized based on two or more abnormal beryllium lymphocyte proliferation tests. Eight of 19 sensitized individuals underwent full clinical evaluation, of whom two were diagnosed with chronic beryllium disease (CBD). Notably, seven beryllium sensitized and CBD cases were hired after the start of cleanup operations. Beryllium medical surveillance detects sensitization and CBD in cleanup workers. Exposure controls and medical surveillance need to be 'broad-based' to include all cleanup workers involved in beryllium-contaminated building remediation. |
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Authors:
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Holly M Sackett; Lisa A Maier; Lori J Silveira; Margaret M Mroz; Lorraine G Ogden; James R Murphy; Lee S Newman |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine Volume: 46 ISSN: 1076-2752 ISO Abbreviation: J. Occup. Environ. Med. Publication Date: 2004 Sep |
Date Detail:
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Created Date: 2004-09-08 Completed Date: 2004-11-02 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9504688 Medline TA: J Occup Environ Med Country: United States |
Other Details:
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Languages: eng Pagination: 953-61 Citation Subset: IM |
Affiliation:
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Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, Denver, CO 80206, USA. SackettH@njc.org |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Berylliosis / diagnosis, epidemiology*, immunology Beryllium / analysis* Chi-Square Distribution Colorado / epidemiology Female Humans Logistic Models Lymphocyte Activation Male Middle Aged Nuclear Warfare* Occupational Exposure / adverse effects* Population Surveillance Respiratory Hypersensitivity / diagnosis, epidemiology*, etiology*, immunology Risk |
| Chemical | |
Reg. No./Substance:
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7440-41-7/Beryllium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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