Document Detail

Benzodiazepines as oral premedicants.
MedLine Citation:
PMID:  6119997     Owner:  NLM     Status:  MEDLINE    
The advantages of the benzodiazpines as oral premedicants are: clear anxiolytic and sedative effect; less clear amnesic action which may prevent the recall of the time spent lying on an uncomfortable theatre trolley, but not necessarily recall of the journey to the operating theatre, or induction of anaesthesia; convenient route of administration; long duration of action of 5-8 h which simplifies timing of drug administration; adverse autonomic, hormonal and circulatory system reactions seem to be prevented, thus preventing the stress reaction even before induction of anaesthesia; anticonvulsant and muscle-relaxing actions may be of value in patients receiving local anaesthesia, or in preventing the side-effects of depolarizing muscle relaxants; nausea before and after operation may be decreased; reduced frequency of side-effects before and after operation.
J Kanto
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  British journal of anaesthesia     Volume:  53     ISSN:  0007-0912     ISO Abbreviation:  Br J Anaesth     Publication Date:  1981 Nov 
Date Detail:
Created Date:  1982-04-22     Completed Date:  1982-04-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0372541     Medline TA:  Br J Anaesth     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  1179-88     Citation Subset:  IM    
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MeSH Terms
Administration, Oral
Anti-Anxiety Agents / administration & dosage*,  metabolism,  therapeutic use
Anxiety / drug therapy
Child, Preschool
Drug Interactions
Hypnotics and Sedatives
Infant, Newborn
Memory / drug effects
Preanesthetic Medication*
Sleep / drug effects
Reg. No./Substance:
0/Anti-Anxiety Agents; 0/Hypnotics and Sedatives; 12794-10-4/Benzodiazepines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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