Document Detail

Benzodiazepine withdrawal: overview and implications for the treatment of anxiety.
MedLine Citation:
PMID:  2897789     Owner:  NLM     Status:  MEDLINE    
The authors critically review 20 reports (studies and large case series) detailing the nature, severity, and variability of benzodiazepine withdrawal syndromes. Factors affecting the frequency and intensity of withdrawal are identified, and methodologic problems limiting the generalizability of certain findings are pointed out. Treatment approaches for minimizing withdrawal are reviewed, and implications for the problem of long-term benzodiazepine use and dependence are discussed.
P P Roy-Byrne; D Hommer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The American journal of medicine     Volume:  84     ISSN:  0002-9343     ISO Abbreviation:  Am. J. Med.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-06-28     Completed Date:  1988-06-28     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1041-52     Citation Subset:  AIM; IM    
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle.
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MeSH Terms
Anti-Anxiety Agents / adverse effects*,  therapeutic use
Anxiety Disorders / drug therapy
Substance Withdrawal Syndrome* / physiopathology,  therapy
Reg. No./Substance:
0/Anti-Anxiety Agents; 12794-10-4/Benzodiazepines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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