Document Detail

Benzene exposure monitoring of Tunisian workers.
MedLine Citation:
PMID:  12500460     Owner:  NLM     Status:  MEDLINE    
To monitor benzene exposure and to check reliability of urinary trans,trans-Muconic Acid (t,t-MA) as a bio-marker of benzene exposure in local conditions, a study was conducted on 30 Tunisian exposed workers (20 tanker fillers and 10 filling station attendants). The analyses were carried out on environmental air and urinary t,t-MA before (t,t-MAA) and at the end of work shift (t,t-MAB). 20 nonoccupationally exposed subjects were also investigated. The average value of environmental benzene concentration was 0.17 ppm. The differences between t,t-MAA and t,t-MAB concentrations and between t,t-MAB and t,t-MA measured in controls (t,t-MAC) were both significant (p < 0.001). Benzene air concentrations were well correlated with t,t-MAB: R = 0.76. In the nonexposed group, average t,t-MA concentrations is significantly higher among smokers than nonsmokers (P < 0.02). Analysis of urinary t,t-MA offers a relatively simple and suitable method for benzene exposure monitoring.
Radhouane Chakroun; Néziha Kaabachi; Abderrazek Hedhili; Moncef Feki; Habib Nouaigui; Mohamed Ben Laiba; Abderraouf Mebazaa
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine     Volume:  44     ISSN:  1076-2752     ISO Abbreviation:  J. Occup. Environ. Med.     Publication Date:  2002 Dec 
Date Detail:
Created Date:  2002-12-25     Completed Date:  2003-04-17     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9504688     Medline TA:  J Occup Environ Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1173-8     Citation Subset:  IM    
Biology and Occupational Toxicology Laboratories Department at the Institute of Occupational Health and Safety, Tunisia.
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MeSH Terms
Air Pollutants, Occupational / analysis*
Benzene / analysis*,  metabolism
Biological Markers / urine*
Chemical Industry
Cluster Analysis
Environmental Monitoring
Middle Aged
Sorbic Acid / analogs & derivatives*,  analysis
Reg. No./Substance:
0/Air Pollutants, Occupational; 0/Biological Markers; 0/Petroleum; 110-44-1/Sorbic Acid; 505-70-4/muconic acid; 71-43-2/Benzene

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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