Document Detail


Benign transient hyperphosphatasemia of infancy. A common benign scenario, a big concern for a pediatrician.
MedLine Citation:
PMID:  21175092     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Benign transient hyperphosphatasemia of infancy (BTH) is a condition characterized by disproportionately high levels of serum alkaline phosphatase (SAP). We report 4 cases of healthy patients with an elevated SAP. The mean age of the patients was 33 (14-52) months, with three females and one male. All children had a normal physical exam and anthropometric measures. The maximum values of serum alkaline phosphatase recorded in the 4 patients were: 11900, 6500, 9700 and 7600 UI/L respectively, with the rest of the laboratory exams and diagnostic images being normal. The clinical course of all the patients was favourable and no patient presented signs of symptoms of illness. Blood was drawn on 6 occasions in patients 1 and 5 occasions in the rest. Benign transient hyperphosphatasemia of infancy was diagnosed. It is important to know the characteristics of this condition to order the necessary amount of complementary studies.
Authors:
Alfredo Eymann; Nicolás Cacchiarelli; Guillermo Alonso; Julián Llera
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric endocrinology & metabolism : JPEM     Volume:  23     ISSN:  0334-018X     ISO Abbreviation:  J. Pediatr. Endocrinol. Metab.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-12-22     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508900     Medline TA:  J Pediatr Endocrinol Metab     Country:  England    
Other Details:
Languages:  eng     Pagination:  927-30     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Hospital Italiano de Buenos Aires, Argentina. alfredo.eymann@hospitalitaliano.org.ar
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MeSH Terms
Descriptor/Qualifier:
Alkaline Phosphatase / blood*
Child, Preschool
Female
Humans
Infant
Male
Chemical
Reg. No./Substance:
EC 3.1.3.1/Alkaline Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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