Document Detail

Benign squamous cells with pleomorphic microvilli in urine or bladder washings.
MedLine Citation:
PMID:  6578647     Owner:  NLM     Status:  MEDLINE    
Exfoliated cells in catheterized urine or bladder washings from 40 patients were observed by light microscopy (LM) and by scanning electron microscopy (SEM). The specimens from seven of these patients (six postmenopausal females and one 85-year-old male) contained squamous cells with pleomorphic microvilli (PMV) on their surfaces. Four of these cases had no bladder lesions by cystoscopic examination. Three patients had recurrent papillary transitional-cell carcinoma of the bladder, and the cytologic specimens from two of them contained transitional cells with PMV. The distinction between squamous and transitional cell is readily made by SEM, based primarily on cell shape and thickness. The presence of PMV on otherwise-benign-appearing squamous cells in urine or bladder washing specimens may be a source of confusion in the interpretation of SEM findings. The presence of PMV on exfoliated squamous cells in cytologic material from the human urinary tract does not seem to have the same diagnostic and prognostic significance as the presence of PMV on transitional cells.
T Suzuki; M St John; S M Cohen; G H Friedell
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Acta cytologica     Volume:  27     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    1983 Sep-Oct
Date Detail:
Created Date:  1983-11-23     Completed Date:  1983-11-23     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  497-9     Citation Subset:  IM    
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MeSH Terms
Carcinoma, Transitional Cell / pathology,  urine
Microscopy, Electron, Scanning
Microvilli / ultrastructure*
Middle Aged
Urinary Bladder / ultrastructure*
Urinary Bladder Neoplasms / pathology,  urine
Urine / cytology*
Grant Support

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