Document Detail


Benign metastasizing chondroblastoma: a case report.
MedLine Citation:
PMID:  9477099     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Metastasis of histologically benign chondroblastoma is a rare event. The authors report a new case, 12th in the literature, wherein multiple lung metastases appeared almost simultaneously with the primary lesion in the right talus bone. METHODS: A histologic evaluation of the primary lesion in the talus and the pulmonary metastasis was performed, and an ultrastructural study of the latter was done. Published literature on metastasizing chondroblastoma was reviewed to identify any consistency in the pattern and the outcome. RESULTS: Metastasis of chondroblastoma is uncommon but well known. Although radiologic and histologic aggressive features have been sought, they do not necessarily correlate with the outcome. CONCLUSIONS: Metastasis in chondroblastoma has been insufficiently stressed in the literature, unlike metastasis in giant cell tumors. The purpose of this case report is not only to document this uncommon event (the 12th case of lung metastasis) but also to emphasize that patients with chondroblastoma may have metastasis at presentation. Hence, all patients need to be evaluated regularly from the onset for possible lung metastasis so that deposits can be detected early for total resection.
Authors:
N A Jambhekar; P B Desai; D A Chitale; P Patil; S Arya
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Cancer     Volume:  82     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1998 Feb 
Date Detail:
Created Date:  1998-03-05     Completed Date:  1998-03-05     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  675-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Pathology, Tata Memorial Hospital, Parel, Bombay, India.
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Neoplasms / pathology*,  radiography,  surgery
Cell Nucleus / ultrastructure
Chondroblastoma / pathology,  radiography,  secondary*,  surgery
Female
Giant Cells / ultrastructure
Humans
Lung Neoplasms / radiography,  secondary*,  surgery,  ultrastructure
Osteoclasts / cytology
Radiography, Thoracic
Talus / pathology,  radiography
Thoracotomy

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