Document Detail


Benign melanocytic tumor in infancy: discussion on a rare case and review of the literature.
MedLine Citation:
PMID:  10965270     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Meningeal melanocytoma is an infrequent neoplasm of the central nervous system (CNS), especially in childhood and infancy. It was first described as an entity different from pigmented meningiomas and schwannomas in 1972, and few cases have been published so far. In this article, a 5-month-old male patient with meningeal melanocytoma is presented. This midline lesion was localized in the posterior fossa and manifested by hydrocephalus. The entire dural origin and extradural growing pattern in addition to the destruction of the adjacent occipital bone were the unexpected presentations since these tumors usually tend to locate on leptomeninges and to extend into the adjacent neural compartment rather than the outside. On the other hand, this case is the only one which had identical lesions in both surrenal glands and the left renal capsule, the structures containing neural-crest-derived cells outside the CNS. The prognostic criteria, differential diagnosis and its embryological aspects are discussed with an extensive review of the related existing literature.
Authors:
H H Oruckaptan; F Soylemezoglu; T Kutluk; N Akalan
Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Pediatric neurosurgery     Volume:  32     ISSN:  1016-2291     ISO Abbreviation:  Pediatr Neurosurg     Publication Date:  2000 May 
Date Detail:
Created Date:  2000-11-21     Completed Date:  2000-11-21     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9114967     Medline TA:  Pediatr Neurosurg     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  240-7     Citation Subset:  IM    
Copyright Information:
Copyright 2000 S. Karger AG, Basel.
Affiliation:
Department of Neurosurgery, Oncology Division, Hacettepe University, School of Medicine, Ankara, Turkey.
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / pathology*
Diagnosis, Differential
Humans
Hydrocephalus / etiology
Immunohistochemistry
Infant
Magnetic Resonance Imaging
Male
Melanocytes / pathology
Melanoma / complications,  diagnosis*,  pathology
Meningeal Neoplasms / complications,  diagnosis*,  pathology
Meningioma / complications,  diagnosis*,  pathology
Neuroectodermal Tumor, Melanotic / complications,  diagnosis*,  pathology
Tumor Markers, Biological / analysis
Chemical
Reg. No./Substance:
0/Tumor Markers, Biological

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