| Benign and malignant musculoskeletal lesions: dynamic contrast-enhanced MR imaging--parametric "first-pass" images depict tissue vascularization and perfusion. | |
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MedLine Citation:
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PMID: 8058957 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To assess the diagnostic value of parametric magnetic resonance images that display the first pass (FP) of gadopentetate dimeglumine. MATERIALS AND METHODS: Dynamic, contrast material-enhanced, fast low-angle shot MR imaging was performed of 100 musculoskeletal lesions in 36 female and 64 male patients (aged 9-81 years [mean, 34 years]). The highest slope value of the time-intensity curve was calculated pixel by pixel and displayed on the FP image, with a gray-scale value equal to the slope value. Tissue vascularization and perfusion were evaluated at pathologic and angiographic examinations in 33 lesions. RESULTS: A significant difference (P < .001) was found between the FP slope values of benign (mean, 36.2% per second) and malignant (mean, 67.4% per second) lesions. FP images depicted tissue vascularization and perfusion rather than benignity or malignancy, because there is an overlap in the slope values of highly vascular benign lesions and malignant lesions. CONCLUSION: FP images provide diagnostically useful information by depicting tissue vascularization and perfusion. |
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Authors:
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K L Verstraete; Y De Deene; H Roels; A Dierick; D Uyttendaele; M Kunnen |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 192 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1994 Sep |
Date Detail:
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Created Date: 1994-09-13 Completed Date: 1994-09-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 835-43 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Gent University Hospital, Belgium. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Bone Diseases / diagnosis* Bone Neoplasms / blood supply, diagnosis Bone and Bones / blood supply Child Contrast Media Drug Combinations Female Gadolinium DTPA Humans Magnetic Resonance Imaging* / methods Male Meglumine / diagnostic use* Middle Aged Muscles / blood supply Muscular Diseases / diagnosis* Organometallic Compounds / diagnostic use* Pentetic Acid / analogs & derivatives*, diagnostic use Sensitivity and Specificity Soft Tissue Neoplasms / diagnosis |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Drug Combinations; 0/Organometallic Compounds; 6284-40-8/Meglumine; 67-43-6/Pentetic Acid; 80529-93-7/Gadolinium DTPA |
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