| Benign intracranial hypertension in chronic myeloid leukemia. | |
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MedLine Citation:
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PMID: 8260157 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We present a patient with chronic myeloid leukemia (CML) who had marked bilateral disc swelling as part of his initial presentation. This occurred in the setting of raised intracranial pressure (ICP), with normal cerebrospinal fluid (CSF) composition and cell content, and normal neuroimaging. We discuss the possible mechanisms which could lead to disc swelling in CML and conclude that the raised ICP and subsequent papilloedema in our patient were the result of poor absorption of CSF into the dural venous sinuses. We propose that the very high white cell count (WCC) led to a hyperviscosity state which resulted in poor absorption of CSF and in so doing, created a clinical picture of benign intracranial hypertension (BIH). |
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Authors:
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R H Guymer; J D Cairns; J O'Day |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Australian and New Zealand journal of ophthalmology Volume: 21 ISSN: 0814-9763 ISO Abbreviation: Aust N Z J Ophthalmol Publication Date: 1993 Aug |
Date Detail:
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Created Date: 1994-01-27 Completed Date: 1994-01-27 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8505423 Medline TA: Aust N Z J Ophthalmol Country: AUSTRALIA |
Other Details:
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Languages: eng Pagination: 181-5 Citation Subset: IM |
Affiliation:
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St Vincent's Hospital, Fitzroy, Victoria. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Cell Count Blood Pressure Bone Marrow / pathology Fluorescein Angiography Fundus Oculi Humans Karyotyping Leukemia, Myelogenous, Chronic, BCR-ABL Positive / complications*, pathology Leukocyte Count Male Papilledema / complications Pseudotumor Cerebri / etiology*, pathology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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