Document Detail


Benign intracranial hypertension during prednisolone treatment for inflammatory bowel disease.
MedLine Citation:
PMID:  8150359     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Benign intracranial hypertension (BIH, pseudotumour cerebri) is a rare condition with unknown aetiology although hormonal influences have been implicated. It occurs spontaneously, particularly in young obese women, and is associated with several drug treatments including corticosteroids. Two young adult women are described in whom headache and papilloedema in association with raised intracranial pressure occurred during prednisolone treatment for inflammatory bowel disease. This provides further evidence of the risk of BIH during corticosteroid treatment and has not been described before in adults with this condition. Advice is given to gastroenterologists to use corticosteroids with caution in adults, particularly young, fertile female patients. The treatment of a severe relapse of colitis in a patient who has had one episode of steroid related BIH remains a dilemma.
Authors:
M Newton; B T Cooper
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Gut     Volume:  35     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1994 Mar 
Date Detail:
Created Date:  1994-05-12     Completed Date:  1994-05-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  423-5     Citation Subset:  AIM; IM    
Affiliation:
Gastroenterology Unit, Dudley Road Hospital, Birmingham.
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MeSH Terms
Descriptor/Qualifier:
Adult
Colitis, Ulcerative / drug therapy
Crohn Disease / drug therapy
Female
Headache / chemically induced
Humans
Inflammatory Bowel Diseases / drug therapy*
Papilledema / chemically induced
Prednisolone / adverse effects*
Pseudotumor Cerebri / chemically induced*
Chemical
Reg. No./Substance:
50-24-8/Prednisolone
Comments/Corrections
Comment In:
Gut. 1994 Nov;35(11):1677   [PMID:  7829001 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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