Document Detail


Benign fasciculations responsive to gabapentin.
MedLine Citation:
PMID:  18094867     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fasciculations are symptoms present in a broad spectrum of conditions, ranging from normal manifestations to motor neuron diseases. They also represent the main picture of benign fasciculation syndrome. We report a case of such syndrome: a 48-years-old woman complaining about fasciculations for three decades who remained with the symptoms even after the compensation of a disclosed hyperthyroidism. The introduction of gabapentin rendered control of her fasciculations. The available data in the literature about the therapeutic approaches for fasciculations are revised, as long as the rare reports of evolution from patients with "benign" fasciculations to cases of amyotrophic lateral sclerosis, underlining the importance of following the patients with fasciculations.
Authors:
Cassiano Mateus Forcelini; Francisco Tellechea Rotta; Naiana Posenato; Joana Stella Rovani; Paulo Sérgio Crusius; Adroaldo Baseggio Mallmann; Cláudio Albano Seibert; Marcelo Ughini Crusius; Charles Carazzo; Cassiano Ughini Crusius; Eduardo Goellner; Jean Ragnini; Sâmia Yasin Wayhs
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Arquivos de neuro-psiquiatria     Volume:  65     ISSN:  0004-282X     ISO Abbreviation:  Arq Neuropsiquiatr     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-12-20     Completed Date:  2008-06-02     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0125444     Medline TA:  Arq Neuropsiquiatr     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  1015-7     Citation Subset:  IM    
Affiliation:
Institute of Neurology and Neurosurgery, Rua Paissandu 1644/302, Passo Fundo, RS, Brazil. cassianoforcelini@brturbo.com.br
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MeSH Terms
Descriptor/Qualifier:
Amines / therapeutic use*
Anticonvulsants / therapeutic use*
Cyclohexanecarboxylic Acids / therapeutic use*
Fasciculation / diagnosis,  drug therapy*
Female
Humans
Middle Aged
gamma-Aminobutyric Acid / therapeutic use*
Chemical
Reg. No./Substance:
0/Amines; 0/Anticonvulsants; 0/Cyclohexanecarboxylic Acids; 56-12-2/gamma-Aminobutyric Acid; 60142-96-3/gabapentin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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