Document Detail

Benign cephalic histiocytosis with diabetes insipidus.
MedLine Citation:
PMID:  10990580     Owner:  NLM     Status:  MEDLINE    
Benign cephalic histiocytosis is a rare skin condition consisting of small tan papules on the face and upper trunk that is believed not to be associated with internal organ involvement. The infiltrating histiocytes are not Langerhans' cells (LCs). We report a 5-year-old girl who presented with diabetes insipidus 1 year after developing multiple small brown asymptomatic skin papules. Histologic examination revealed a non-LC histiocytic proliferation in the dermis without epidermal invasion. She had infiltration of the pituitary stalk on brain imaging. Diabetes insipidus has heretofore been associated with LC histiocytosis and xanthoma disseminatum but not benign cephalic histiocytosis.
W L Weston; S H Travers; G W Mierau; D Heasley; J Fitzpatrick
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pediatric dermatology     Volume:  17     ISSN:  0736-8046     ISO Abbreviation:  Pediatr Dermatol     Publication Date:    2000 Jul-Aug
Date Detail:
Created Date:  2000-10-02     Completed Date:  2000-10-02     Revised Date:  2009-03-03    
Medline Journal Info:
Nlm Unique ID:  8406799     Medline TA:  Pediatr Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  296-8     Citation Subset:  IM    
Departments of Dermatology and Pediatrics, University of Colorado School of Medicine, and Department of Pathology, Children's Hospital, Denver, Denver, Colorado, USA.
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MeSH Terms
Child, Preschool
Diabetes Insipidus / complications*
Histiocytosis, Non-Langerhans-Cell / complications,  pathology*
Skin / pathology,  ultrastructure
Skin Diseases / complications,  pathology*

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