| Benefits of salmon eating on traditional and novel vascular risk factors in young, non-obese healthy subjects. | |
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MedLine Citation:
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PMID: 17069820 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIM: The present clinical study tested the hypothesis that oil-rich fish consumption improves CHD risk factors. METHODS: Forty-eight (16 men) non-obese, healthy adults aged 20-55, consumed 125 g/day of salmon for a 4-week period followed by a 4-week period with no-fish (41 completers). Subjects were instructed to maintain dietary and physical activity patterns during the period of study. Blood pressure, anthropometric, body composition and dietary information with fasting blood samples to determine traditional and novel CHD risk markers and plasma fatty acids were obtained before and after each period. RESULTS: Compared to no-fish, eating salmon significantly decreased systolic, diastolic and mean arterial blood pressure by 4%, triglycerides by 15%, and LDL-cholesterol by 7%, and significantly increased HDL-cholesterol by 5% (P<0.05). The changes in blood pressure and lipids alone with salmon intake predict around a 25% reduction in CHD risk based on the PROCAM risk calculator. Plasma adiponectin demonstrated a trend towards improvement (8.39 micromol/L with salmon and 7.52 with no-fish; P=0.086) but no significant changes were found either in plasma leptin, glucose or insulin after salmon consumption. CONCLUSIONS: Daily consumption of salmon improves traditional risk predictors of CHD in non-obese subjects. Adiponectin may be involved but the impact on novel risk factors needs study in high-risk subjects. |
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Authors:
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Jose J Lara; Maria Economou; A Michael Wallace; Anne Rumley; Gordon Lowe; Christine Slater; Muriel Caslake; Naveed Sattar; Michael E J Lean |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-10-27 |
Journal Detail:
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Title: Atherosclerosis Volume: 193 ISSN: 0021-9150 ISO Abbreviation: Atherosclerosis Publication Date: 2007 Jul |
Date Detail:
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Created Date: 2007-05-28 Completed Date: 2007-08-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0242543 Medline TA: Atherosclerosis Country: Ireland |
Other Details:
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Languages: eng Pagination: 213-21 Citation Subset: IM |
Affiliation:
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Department of Human Nutrition, Division of Developmental Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, Scotland, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Blood Pressure Cholesterol, HDL / blood Cholesterol, LDL / blood Coronary Disease / blood, etiology, physiopathology, prevention & control* Diet* Dietary Fats, Unsaturated / administration & dosage Female Fish Oils / administration & dosage Humans Lipids / blood Male Middle Aged Risk Factors Salmon* Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Dietary Fats, Unsaturated; 0/Fish Oils; 0/Lipids; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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