| Benefits and problems with cloning animals. | |
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MedLine Citation:
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PMID: 11143925 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Animal cloning is becoming a useful technique for producing transgenic farm animals and is likely to be used to produce clones from valuable adults. Other applications will also undoubtedly be discovered in the near future, such as for preserving endangered breeds and species. Although cloning promises great advantages for commerce and research alike, its outcome is not always certain due to high pregnancy losses and high morbidity and mortality during the neonatal period. Research into the mechanisms involved in the reprogramming of the nucleus is being conducted throughout the world in an attempt to better understand the molecular and cellular mechanisms involved in correcting these problems. Although the cause of these anomalies remains mostly unknown, similar phenotypes have been observed in calves derived through in vitro fertilization, suggesting that culture conditions are involved in these phenomena. In the meantime, veterinarians and theriogenologists have an important role to play in improving the efficiency of cloning by finding treatments to assure normal gestation to term and to develop preventative and curative care for cloned neonates. |
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Authors:
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L C Smith; V Bordignon; M Babkine; G Fecteau; C Keefer |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Canadian veterinary journal. La revue vétérinaire canadienne Volume: 41 ISSN: 0008-5286 ISO Abbreviation: Can. Vet. J. Publication Date: 2000 Dec |
Date Detail:
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Created Date: 2000-12-18 Completed Date: 2001-01-18 Revised Date: 2010-09-14 |
Medline Journal Info:
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Nlm Unique ID: 0004653 Medline TA: Can Vet J Country: Canada |
Other Details:
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Languages: eng Pagination: 919-24 Citation Subset: IM |
Affiliation:
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Centre de recherche en reproduction animale, Faculté de médicine vétérinaire, Université de Montréal, Saint-Hyacinthe, Quebec J2S 7C6. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animal Husbandry* Animals Animals, Newborn Cattle Cloning, Organism* Conservation of Natural Resources Female Fetal Death / veterinary Forecasting Genetic Diseases, Inborn / prevention & control, veterinary* Male Pregnancy Veterinary Medicine / trends |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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