Document Detail


Benefits of placental biopsies for rapid karyotyping in the second and third trimesters (late chorionic villus sampling) in high-risk pregnancies.
MedLine Citation:
PMID:  2187349     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a total of 301 placental biopsies in the second and third trimesters, 225 were performed because of suspicious ultrasonographic findings. In this group there was a high rate of aneuploidies (20%). As opposed to the alternative methods for rapid karyotyping, placental biopsies can easily be performed even in pregnancies with abnormal amounts of amniotic fluid. Oligohydramnios and polyhydramnios were key ultrasonographic findings in 38% of cases and were found to be associated with 22% of abnormal chromosomal findings. Suggestive ultrasonographic findings seem to justify the exclusive use of direct preparation.
Authors:
W Holzgreve; P Miny; B Gerlach; A Westendorp; D Ahlert; J Horst
Related Documents :
20445129 - Maternal undernutrition influences placental-fetal development.
2020749 - Arachidonic acid metabolism by bovine placental tissue during the last month of pregnancy.
9360539 - Expression of somatostatin receptor sst4 in human placenta and absence of octreotide ef...
14522419 - Placental infection with chlamydia pneumoniae and intrauterine growth restriction.
12513889 - Placental transfer of cotinine at 12-17 weeks of gestation and at term in heavy smokers.
2403179 - Lack of specific placental abnormality associated with cocaine use.
20613669 - Effects of age at first pregnancy and breast-feeding on the development of postmenopaus...
21962149 - The predictive value of leukocyte parameters for hypertensive disorders of pregnancy in...
18797269 - Intrauterine devices and adolescents.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  162     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-15     Completed Date:  1990-06-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1188-92     Citation Subset:  AIM; IM    
Affiliation:
Zentrum für Frauenheilkunde, Münster, FRG.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Amniotic Fluid
Aneuploidy
Chorionic Villi Sampling* / methods
Chromosome Aberrations / diagnosis*,  genetics
Chromosome Disorders
Female
Fetal Diseases / diagnosis*,  genetics
Humans
Karyotyping
Polyhydramnios / diagnosis
Pregnancy
Pregnancy Trimester, Second
Pregnancy Trimester, Third
Prenatal Diagnosis
Risk Factors
Ultrasonography

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Serum fructosamine and amniotic fluid insulin levels in patients with gestational diabetes and healt...
Next Document:  Flow velocity waveforms in uterine and umbilical arteries during the angiotensin II sensitivity test...