Document Detail


Benefits and costs of methadone treatment: results from a lifetime simulation model.
MedLine Citation:
PMID:  15880389     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Several studies have examined the benefits and costs of drug treatment; however, they have typically focused on the benefits and costs of a single treatment episode. Although beneficial for certain analyses, the results are limited because they implicitly treat drug abuse as an acute problem that can be treated in one episode. We developed a Monte Carlo simulation model that incorporates the chronic nature of drug abuse. Our model represents the progression of individuals from the general population aged 18-60 with respect to their heroin use, treatment for heroin use, criminal behavior, employment, and health care use. We also present three model scenarios representing an increase in the probability of going to treatment, an increase in the treatment length of stay, and a scenario in which drug treatment is not available to evaluate how changes in treatment parameters affect model results. We find that the benefit-cost ratio of treatment from our lifetime model (37.72) exceeds the benefit-cost ratio from a static model (4.86). The model provides a rich characterization of the dynamics of heroin use and captures the notion of heroin use as a chronic recurring condition. Similar models can be developed for other chronic diseases, such as diabetes, mental illness, or cardiovascular disease.
Authors:
Gary A Zarkin; Laura J Dunlap; Katherine A Hicks; Daniel Mamo
Related Documents :
17680639 - Measuring low back injury risk factors in challenging work environments: an evaluation ...
16229669 - Science and pseudoscience in communication disorders: criteria and applications.
18397929 - Mitigation of ineffective measures against radon.
20491849 - Hunter reporting of catch per unit effort as a monitoring tool in a bushmeat-harvesting...
11569789 - Costs of sexual traits: a mismatch between theoretical considerations and empirical evi...
10393489 - Towards better decision making in growth hormone therapy.
15186769 - Flagellar biosynthesis in silico: building quantitative models of regulatory networks.
25235249 - Uncertainty aspects regarding the input for reverberation time predictions.
1795649 - Qsar prediction of rodent carcinogenicity for a set of chemicals currently bioassayed b...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Health economics     Volume:  14     ISSN:  1057-9230     ISO Abbreviation:  Health Econ     Publication Date:  2005 Nov 
Date Detail:
Created Date:  2005-10-24     Completed Date:  2006-01-18     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  9306780     Medline TA:  Health Econ     Country:  England    
Other Details:
Languages:  eng     Pagination:  1133-50     Citation Subset:  IM    
Affiliation:
RTI International, Research Triangle Park, NC 27709, USA. gaz@rti.org
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Cost-Benefit Analysis
Crime
Employment
Female
Health Services / utilization
Heroin Dependence / drug therapy,  economics*
Humans
Male
Methadone / economics*,  therapeutic use
Middle Aged
Monte Carlo Method
Narcotics / economics*,  therapeutic use
Grant Support
ID/Acronym/Agency:
R01-DA12420/DA/NIDA NIH HHS; R01-DA15655/DA/NIDA NIH HHS
Chemical
Reg. No./Substance:
0/Narcotics; 76-99-3/Methadone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Structural and dynamic properties of cytochrome P450 BM-3 in pure water and in a dimethylsulfoxide/w...
Next Document:  Endoscopic-assisted cranionasal resection of olfactory neuroblastoma.