Document Detail


Benefit-risk analysis for the clinician: 'primum non nocere' revisited--the case for antipsychotics in the treatment of behavioural disturbances in dementia.
MedLine Citation:
PMID:  20391588     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The results of clinical trials are often presented in a way that only highlights either the benefits or the risks of the treatment under study. Especially in older age, clinical psychiatric problems are often of complex nature, which requires integrating multiple sources of data to reach clinical decisions. An analytical, decision-making strategy can be of help in arranging the results of various studies in such a way as to aid decision-making. In this paper, we clarify this method using the case of the risks and benefits of using antipsychotics in older people with dementia and behavioural disturbances.
Authors:
P Naarding; M van Grevenstein; A T F Beekman
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Publication Detail:
Type:  Editorial    
Journal Detail:
Title:  International journal of geriatric psychiatry     Volume:  25     ISSN:  1099-1166     ISO Abbreviation:  Int J Geriatr Psychiatry     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-04-14     Completed Date:  2011-01-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710629     Medline TA:  Int J Geriatr Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  437-40     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Antipsychotic Agents / adverse effects,  therapeutic use*
Decision Making*
Decision Support Techniques*
Dementia / drug therapy*,  psychology
Hippocratic Oath
Humans
Mental Disorders / drug therapy*
Risk Assessment
Chemical
Reg. No./Substance:
0/Antipsychotic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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