| Beneficial effects of a Dietary Approaches to Stop Hypertension eating plan on features of the metabolic syndrome. | |
| | |
MedLine Citation:
|
PMID: 16306540 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To determine the effects of a Dietary Approaches to Stop Hypertension (DASH) eating plan on metabolic risks in patients with the metabolic syndrome. RESEARCH DESIGN AND METHODS: This was a randomized controlled outpatient trial conducted on 116 patients with the metabolic syndrome. Three diets were prescribed for 6 months: a control diet, a weight-reducing diet emphasizing healthy food choices, and the DASH diet with reduced calories and increased consumption of fruit, vegetables, low-fat dairy, and whole grains and lower in saturated fat, total fat, and cholesterol and restricted to 2,400 mg Na. The main outcome measures were the components of the metabolic syndrome. RESULTS: Relative to the control diet, the DASH diet resulted in higher HDL cholesterol (7 and 10 mg/dl), lower triglycerides (-18 and -14 mg/dl), systolic blood pressure (SBP) (-12 and -11 mmHg), diastolic blood pressure (-6 and -7 mmHg), weight (-16 and -14 kg), fasting blood glucose (FBG) (-15 and -8 mg/dl), and weight (-16 and -15 kg), among men and women, respectively (all P < 0.001). The net reduction in triglycerides (-17 and -18 mg/dl), SBP (-11 and -11 mmHg), diastolic blood pressure (-5 and -6 mmHg), and FBG (-4 and -6 mg/dl), weight (-16 and -15 kg), and increase in HDL (5 and 10 mg/dl) among men and women, respectively, was higher in the DASH group (all P < 0.05). The weight-reducing diet resulted in significant change in triglycerides (-13 and -10 mg/dl), SBP (-6 and -6 mmHg), and weight (-13 and -12 kg) among men and women, respectively (all P < 0.05). CONCLUSIONS: The DASH diet can likely reduce most of the metabolic risks in both men and women; the related mechanisms need further study. |
| | |
Authors:
|
Leila Azadbakht; Parvin Mirmiran; Ahmad Esmaillzadeh; Tohid Azizi; Fereidoun Azizi |
Publication Detail:
|
Type: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Diabetes care Volume: 28 ISSN: 0149-5992 ISO Abbreviation: Diabetes Care Publication Date: 2005 Dec |
Date Detail:
|
Created Date: 2005-11-24 Completed Date: 2006-01-31 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7805975 Medline TA: Diabetes Care Country: United States |
Other Details:
|
Languages: eng Pagination: 2823-31 Citation Subset: IM |
Affiliation:
|
Endocrine Research Center, Shaheed Beheshti University of Medical Sciences, P.O. Box 19395-4763, Tehran, Iran. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Body Weight Cholesterol, HDL / blood Diet* Diet, Reducing* Energy Intake Female Humans Hypertension / blood, diet therapy*, prevention & control* Male Metabolic Syndrome X / blood, diet therapy*, prevention & control* Middle Aged Outpatients Reproducibility of Results |
| Chemical | |
Reg. No./Substance:
|
0/Cholesterol, HDL |
| Comments/Corrections | |
Comment In:
|
Diabetes Care. 2006 Apr;29(4):954; author reply 954-5
[PMID:
16602197
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Decreasing the risk of diabetic retinopathy in a study of case management: the California Medi-Cal T...
Next Document: Dietary glycemic index and glycemic load, carbohydrate and fiber intake, and measures of insulin sen...